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Authors
Affiliations
1 Division of Veterinary Pathology, Shuhama, Alusteng, Sher‑e‑Kashmir University of Agricultural Sciences, Kashmir, IN
Source
Nature Environment and Pollution Technology, Vol 15, No 2 (2016), Pagination: 635-639
Abstract
The present work was conducted to elucidate the haematological changes in broiler chickens after Ziram intoxication. For this study, 150 apparently healthy broiler chicks were reared up to 2 weeks of age and randomly allocated to four groups, i.e. acute (N=10), sub-acute (N=20), sub-chronic (N=90) and control (N=30). Toxicity was induced following a single oral dose of Ziram @ 100mg/kg body weight for acute intoxication; 5 mg/kg body weight per day for 20 days in case of sub-acute group and 1mg/kg body weight per day for the study period of 90 days in case of sub-chronic intoxication. At the end of the experimental period the investigations revealed significant decrease in haemoglobin concentration, packed cell volume, total erythrocyte count and leucocytosis with heterophilia leading to clinical anaemia.
Keywords
Broiler Chickens, Ziram Fungicide, Toxicity, Haematology.
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References
- Ajaz 2010. How to minimize the use of pesticide in the farming system. www.greaterkashmir.com.
- Casale, P. 1989. Effect of carbofuran in sheep. Fundamental Applied Toxicology, 12(3): 460-68.
- Chesterman, H., Heywood, R., Ball, S., Street, A. and Prentice, D. 1998. Metiram oral toxicity study in beagle dogs for period of 4 weeks. Submitted to World Health Organisation by BASF Corporation Limited.
- Dickhaus, S. and Heisler, E. 1980. Report of subacute toxicity study on ziram for four weeks in the Rat. Report No. 2-4-132-80 from Pharmatox, Germany.
- Edwards, I.R., Ferry, D. and Temple, A. 1991. Fungicides and Related Compounds. In: Hayes WJ, Laws ER, editors. Handbook of Pesticide Toxicology. New York: Academic Press, Inc.
- Kanchi, S. 2013. Dithiocarbamates as hazardous remediation agent. Arabian Journal of Chemistry, 7(1): 11-25.
- Michael, K. 1997. Toxicity of pesticides and its impact on environment. Environmental Sciences and Agriculture, pp. 143-147.
- Rasul, A.R. and Howell, J.M. 1974. The toxicity of some dithiocarbamate compounds in young and adult domestic fowl. Toxicology & Applied Pharmacology, 31(1): 63-78.
- Van Leeuwen, C.J., Van Hameren, P., Bogers, M. and Griffionen, P.S. 1986. Uptake, distribution and retention of zineb and ziram in rainbow trout (Salmo gairdneri). Toxicology, 42(1): 33-46.
- Yousef, M. and Al-Salhen, K. 2003. Changes in some hematological and biochemical indices of rabbits induced by isoflavones and cypermethrin. Toxicology, 189(3): 223-234.
